Hot Shots
In order to "save" Stewie from autism, Peter and Lois decide not to vaccinate him and then proceed to convince the rest of Quahog to follow suit. Stewie runs away to save himself from diseases until Sean Penn swoops in to save the day and brings vaccines to the whole town.

Cast
Seth MacFarlanePeter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire (voice)
Alex BorsteinLois Griffin / Tricia Takanawa / Loretta Brown / Barbara Pewterschmidt (voice)
Mila KunisMeg Griffin (voice)
Seth GreenChris Griffin (voice)
Patrick WarburtonJoe Swanson (voice)
Arif ZahirCleveland Brown (voice)Family Guy on tvt

